Skip to main content
Figure 7 | Geochemical Transactions

Figure 7

From: Calculation of the relative metastabilities of proteins using the CHNOSZ software package

Figure 7

Metastabilities of proteins around a pseudoinvariant point. Activities of CO2(aq), NH3(aq), H2S(aq) and H2O were calculated using a buffer consisting of the proteins from the METXX organisms listed in Table 1. The variables set in the buffer calculation were activities of proteins equal to 10-3, T = 100°C, P = 1000 bar, log f O 2 ( g ) MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaemOzay2aaSbaaSqaaiabb+eapnaaBaaameaacqaIYaGmcqGGOaakcqWGNbWzcqGGPaqkaeqaaaWcbeaaaaa@32AE@ = -58 and pH 7. The diagrams show the variation of protein metastability as a function of (a) temperature and pressure and (b) log f O 2 ( g ) MathType@MTEF@5@5@+=feaagaart1ev2aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGaciGaaiaabeqaaeqabiWaaaGcbaGaemOzay2aaSbaaSqaaiabb+eapnaaBaaameaacqaIYaGmcqGGOaakcqWGNbWzcqGGPaqkaeqaaaWcbeaaaaa@32AE@ and pH. The dashed line in (b) represents the lower stability limit of H2O at this temperature and pressure.

Back to article page